"The current systemic acne medications have staying power for one simple
reason - they work," said Dr. Baldwin. "Recently, some exciting new treatments
have expanded our options for acne patients and have even addressed some
of the potential drawbacks of oral acne medications, such as bacterial
resistance with long-term antibiotic use."
Dr. Baldwin reported that one of the most innovative new systemic acne
medications is extended-release minocycline, which is the first time a
weight-based oral medication has been introduced to control acne. This
dose-based medication is taken once per day, and the extended-release
nature of the drug means that the peak serum levels that are obtained
in the bloodstream are not nearly as high as with immediate-release minocycline.
Dr. Baldwin added that it is the peak serum levels in the bloodstream
that is thought to cause the relatively high degree of side effects, such
as dizziness, headaches and nausea.